It's important to recognize, both in lotteries and medicine, you can do things that change a probability by a large amount but with no real-world, practical significance. You can increase the odds of winning that state lottery by a factor of 100 by buying 100 lottery tickets. But the chance of winning remains so incredibly low, 1 in 100,000, that it hardly seems like a reasonable investment. You might read that the probability of getting a disease is reduced by 50% if you accept a particular treatment. But if you only had a 1 in 10,000 chance of getting it anyway, it may not be worth the expense, or the potential side effects, to lower the risk.