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In 2000, a neuroscientist at University College London named Eleanor Maguire wanted to find out what effect, if any, all that driving around the labyrinthine streets of London might have on the cabbies' brains. When she brought sixteen taxi drivers into her lab and examined their brains in an MRI scanner, she found one surprising and important difference. The right posterior hippocampus, a part of the brain known to be involved in spatial navigation, was 7 percent larger than normal in the cabbies--a small but very significant difference. Maguire concluded that all of that way-finding around London had physically altered the gross structure of their brains. The more years a cabbie had been on the road, the more pronounced the effect.